Endocrine Abstracts

Insulin is a thyroid growth factor that stimulates proliferation of thyroid cells in culture. It has been observed that insulin receptors are over expressed in most thyroid tumors as an early step in thyroid carcinogenesis.Eighty women (mean age 36.85±4.71 years) were evaluated by a thyroid ultrasound (US), fasting plasma insulin and HOMA IR. Subjects were divided into four groups as follows: G1 (n: 24),subjects with IR and obesity; G2 (n<...

Recent reports on the interplay between adiponectin, thyroid hormones and metformin have given conflicting results. Our study aimed to investigate adiponectin concentration in thyroid disorders and to assess the possibility of involvement of adiponectin in the regulation of thyroid hormone production, also to clarify the role of pituitary-thyroid axis in the modulation of adiponectin production and to assess the interplay between metformin treatment, thyroid function and adipo...